REYES, Ronald Lazo

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REYES, Ronald Lazo
Specially Appointed Assistant Professor
SAWAMURA, Masaya Group
Principal Investigator
Faculty Members
Postdoctoral Fellows
Research Collaborators

About the Research

Research Theme

Catalytic Asymmetric C–H activation/functionalization enabling the elaboration and diversification of molecules


Asymmetric Synthesis, Organometallic Catalysis, C–H Activation, Borylation
Research Outline

I have been working on the development of transition-metal catalyzed asymmetric C–H bond activation/functionalization to enable the construction of compounds with three-dimensional structural diversity. In particular, I am greatly interested in the elaboration of transformative synthetic strategies that circumvent challenges in the activation of C(sp3)–H bonds. Inspired by the efficiency of enzymes in enabling such challenging transformations, my ultimate dream is to create highly competent synthetic catalysts that can facilitate similar reactivities in a sustainable, green, and atom-economical manner.

Research History

See my CV

Representative Research Achievements

  • Asymmetric Synthesis of -Aminoboronates via Rhodium-Catalyzed Enantioselective C(sp3)–H Borylation
    R. L. Reyes, M. Sato, T. Iwai, and M. Sawamura, J. Am. Chem. Soc., 2020, 142, 589–597
    DOI: 10.1021/jacs.9b12013
  • Iridium-catalyzed Asymmetric Borylation of Unactivated Methylene C(sp3)–H Bonds
    R. L. Reyes, T. Iwai, S. Maeda, and M. Sawamura, J. Am. Chem. Soc., 2019, 141, 6817–6821
    DOI:  10.1021/jacs.9b01952
  • Enantioselective Rh- or Ir-Catalyzed Directed C(sp3)–H Borylation with Phosphoramidite Chiral Ligands
    R. L. Reyes, T. Harada, T. Taniguchi, K. Monde, T. Iwai, and M. Sawamura,
    Chemistry Letters, 2017, 46, 1747–1750
    DOI: 10.1246/cl.170853