MANABIYA

The MANABIYA System

MANABIYA is a system to foster a new generation of researchers proficient in the three fields of computational, information and experimental science and to develop the new interdisciplinary academic field of “Chemical Reaction Design and Discovery (CReDD)” worldwide. Thus, we aim to form an academic network, making ICReDD an internationally recognized research institution, and discover new research seeds.

MANABIYA Academic

Early-career researchers and graduate-level students from domestic and overseas research centers and universities are invited to stay at ICReDD for 2 weeks (minimum) to 3 months (maximum). A model case for six weeks is as follows. The purpose of this system is to help the researchers acquire techniques for developing new chemical reactions. In the course of their study, they are also expected to discover new research seeds. In the future, we aim to establish a brain circulation society where the researchers use and spread the techniques they have acquired at ICReDD.

Please see the FY2023 application guidelines to apply.

Francesco Puccetti, MANABIYA participant

Find out what it is like to come to Japan from abroad for the MANABIYA program by reading our interview with Francesco Puccetti, PhD student at RWTH Aachen University in Germany.

MANABIYA Manuscripts

Participants in the MANABIYA ACADEMIC program acquire skills that are directly applicable to their research. Click the following links below to see publications that include results obtained during the MANABIYA program.

Computationally guided catalyst design for low-temperature methane combustion

Understanding the Ring-Flip Mechanism of Overcrowded Ethylenes through an Experimental and Theoretical Approach

Platinum(II) chiral diene catalyst enables enantioselective [4+2] cycloaddition via Pt(II)/Pt(IV) cycle

Chemoselective Cleavage of Si–C(sp³) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate)

Silane- and peroxide-free hydrogen atom transfer hydrogenation using ascorbic acid and cobalt-photoredox dual catalysis

MANABIYA Industry

In the MANABIYA Industry branch of the program, we promote collaborations between ICReDD faculty and corporate researchers in the form of consulting and research collaborations.

Please refer to the research topics offered by our faculty members below and contact a MANABIYA representative if you are interested in MANABIYA Industry!

MANABIYA Course (6 weeks model case)

The 1st week
MANABIYA researchers will attend AFIR and ICReDD tutorials and discuss specific research goals and requirements with a supervisor.

The 2nd to 5th week
The applicant will be able to work on selected course from below. The MAMABIYA members are encouraged to discuss with PIs in all three fields to solve the problems they encounter in the collaborative research.
Seminars
MAMABIYA members participate in the ICReDD seminars.

The last week
MAMABIYA members summarize the results and deliver presentation for the achievement in ICReDD.
Issuance of MANABIYA Certificate

	MAEDA, Satoshi	AFIR Course (2 – 3 months) Collaborative research on establishing AFIR approaches to the problems and data provided by applicants. Applicants’ experimental/computational problems are collaboratively investigated by discussing the results of calculations and will repeat the discussion and considerations for improvement.
	TAKETSUGU, Tetsuya	Quantum-Chemical Computation Course (2 weeks – 3 months) Collaborative research with advanced quantum chemical computations in Taketsugu lab and ICReDD will be conducted for establishing (1) the desired excited-state reactions and (2) the desired heterogeneous catalytic reactions.
	YAMAMOTO, Tetsuya (Rubinstein group)	Polymer Physics Course Collaborative research on polymer simulations by using the computer cluster in ICReDD or on polymer theory will be conducted to make sense of experimental results on polymer systems, such as polymer networks and gels, which are obtained by the applicant. Genome Physics course Collaborative research will be conducted on the theoretical physics of gene regulation and phenomena in nucleus. Molecular biologists who wish to understand their experimental results on the basis of soft matter physics and biochemical reaction kinetics are encouraged to apply.
	YOSHIOKA, Masaharu	Chemical Information Course (1 month) Collaborative research on utilization of chemical information for analyzing chemical reaction processes by using chemical databases and tools for extracting information from chemical related texts. MANABIYA members are encouraged to discuss with PIs to make a framework to collect useful information related to a particular reaction process from chemical databases and chemical related texts such as research papers and patents.
	STAUB, Ruben (Varnek group)	Advanced Chemical Data Management and Modeling Course (1 – 2 months) Collaborative research using chemoinformatics techniques to model structure-property relationships, create chemical databases and accelerate ab-initio studies.
	TAKIGAWA, Ichigaku	Machine Learning Course (1 month) Collaborative research on establishing ML approaches to the problems and data provided by applicants. Takigawa lab will provide the-state-of-the-art ML related expertise, and methods and practices that best fit to applicants’ experimental/computational problems are collaboratively investigated. Applicants are also encouraged to discuss with PIs in all three fields to solve problems raised during their research.
	KOMATSUZAKI, Tamiki	Molecular Data Science Course (2 – 3 months) Collaborative research using information algorithms in Komatsuzaki lab will be conducted for the applications of algorithms such as reinforcement learning, causal inference, image analysis, quantum computing to establishing a fusing science with computation and experimental sciences.
	IWATA, Satoru	Optimization Course The MANABIYA members are encouraged to raise optimization issues they encounter in research on chemical reactions. Both discrete and continuous aspects are welcome. Through discussions with the PI and other lab members, they will try to formulate the issue as an optimization problem and develop solution methods.
	ITO, Hajime	Mechanosynthesis Course (2 weeks – 1 month) Collaborative research using equipment in Ito lab and ICReDD will be conducted for establishing the desired ball-mill reactions of any solution-based reactions.
	SAWAMURA, Masaya	Asymmetric Metal Catalysis Course The applicants will work on collaborative research on enantioselective transition metal catalysis.
	TSUJI, Nobuya (List group)	Organocatalysis Course (2 – 3 months) The applicants will work on collaborative research on chiral Lewis acid- or Brønsted acid-catalyzed asymmetric transformations.
	INOKUMA, Yasuhide	Polyketone Course (up to 3 months) You can learn how to synthesize discrete polyketones, organic fluorophores, and metal complexes using the experimental labs and equipment in ICReDD.
	HASEGAWA, Yasuchika	Eu Luminophore Course (1 month) Collaborative research using equipment in the Hasegawa lab and ICReDD will be conducted for preparation and photo-physical analysis of Eu luminophores (Eu complexes and coordination polymers).
	GONG, Jian Ping	Soft material Course (1 – 2 months) Collaborative research using equipment in the Gong lab and ICReDD will be conducted for synthesizing and analyzing tough and marine adhesive hydrogels.
	OGAWA, Mikako	Fluorescent Dye Development for Biological Use Course (1, 2, or 3 months) Participants will pursue collaborative research on the synthesis of fluorescent dyes, optical characterization of fluorescent dyes, and evaluation of fluorescent dyes in cultured cells.
	TANAKA, Shinya	Material Genomics course (1, 2, or 3 months) Collaborative research using equipment in the Tanaka lab and learning about cell control machinery of new biomaterials including hydrogels.
	JIN, Mingoo (Jin group)	Crystalline Molecular Rotor and Solid-State Function Course (1 – 3 months) Collaborative research to develop novel molecular rotors and solid-state functions, covering synthesis and characterization using XRD, NMR and various spectrometers.
	SIDOROV, Pavel (Sidorov group)	Chemoinformatics Course (1 – 2 months) Collaborative research using chemoinformatics tools for chemical data management, analysis and QSAR modeling.