About the Research
Research Theme
Integrating Machine Learning in Informatics Tools Development for Data-Driven Science
Keyword
Research Outline
My research focused on using machine learning and literature data mining to predict the potential toxicity or activity of specific nanoparticles or small molecules. Now, I am actively seeking new opportunities and collaborations to further my career in data-driven science. Specifically, I am exploring various machine learning principles and techniques like sequential model-based optimization, geometric deep learning, and image-based deep learning for data-driven scientific research. The core objective is to integrate machine learning methodologies into the development of computational tools. These tools are designed to assist scientists in analyzing large datasets and extracting meaningful insights, particularly in domains such as drug discovery and chemistry.
Representative Research Achievements
- Evidence-Based Prediction of Cellular Toxicity for Amorphous Silica Nanoparticles
Martin, Watanabe, R., Hashimoto, K., Higashisaka, K., Haga, Y., Tsutsumi, Y., Mizuguchi, K. ACS Nano, 2023, 17, 9987–9999.
DOI: 10.1021/acsnano.2c11968 - Safety, efficacy, and cost-effectiveness of insulin degludec U100 versus insulin glargine U300 in adults with type 1 diabetes: a systematic review and indirect treatment comparison
Martin, Zhou, Y., Takagi, T., Tian, YS. Int. J. Clin. Pharm., 2022, 44, 587–598.
DOI: 10.1007/s11096-022-01410-x - Efficacy and safety among second-generation and other basal insulins in adult patients with type 1 diabetes: a systematic review and network meta-analysis
Martin, Zhou, Y., Takagi, T., Tian, YS. Naunyn-Schmiedeberg’s Arch. Pharmacol., 2021, 394, 2091–2101.
DOI: 10.1007/s00210-021-02128-9 - Vonoprazan vs proton pump inhibitors in treating post-endoscopic submucosal dissection ulcers and preventing bleeding: A meta-analysis of randomized controlled trials and observational studies
Martin, Zhou, Y., Meng, CX., Takagi, T., Tian, YS. Medicine, 2020, 99, 9(e19357).
DOI: 10.1097/md.0000000000019357 - Vonoprazan versus proton pump inhibitors in treating post-endoscopic submucosal dissection ulcers and preventing bleeding: Protocol for meta-analysis of randomized controlled trials and observational studies
Martin, Zhou, Y., Meng, CX., Takagi, T., Tian, YS. Medicine, 2019, 98, 8(e14381).
DOI: 10.1097/md.0000000000014381