About the Research
Research Theme
Data analysis automation and predictive modeling
Keyword
De novo drug design, chemoinformatics, data analysis, machine learning
Research History
Please see my CV.
Representative Research Achievements
- Orally Bioavailable 4-Phenoxy-quinoline Compound as a Potent Aurora Kinase B Relocation Blocker for Cancer Treatment
J. Li, T. Zhang, Q. Shi, G. Lv, X. Zhou, N. Choudhry, J. Kalashova, C. Yang, H.Li, Y. Long, S. Balasubramaniyan. ACS Pharmacol. Transl. Sci., 2023, 6, 1155–1163.
DOI: 10.1021/acsptsci.3c00054 - Virtually screened novel sulfathiazole derivatives as a potential drug candidate for methicillin-resistant Staphylococcus aureus and multidrug-resistant tuberculosis
N. Saraswathy, S. Balasubramaniyan, N. Irfan. J. Biomol. Struct. Dyn., 2023, 41, 5086-5095.
DOI: 10.1080/07391102.2022.2079002 - Bioisosteric replacements of tyrosine kinases inhibitors to make potent and safe chemotherapy against malignant cells
N. Irfan, S. Balasubramaniyan, D. Mubarak Ali, A. Puratchikody. J. Biomol. Struct. Dyn., 2022, 41, 9437-9447.
DOI: 10.1080/07391102.2022.2146751 - The synthesis and biological evaluation of virtually designed fluoroquinolone analogs against fluoroquinolone-resistant Escherichia coli intended for UTI treatment
S. Balasubramaniyan, N.Irfan, C. Senthilkumar, A. Umamaheswari, A. Puratchikody. New J. Chem., 2020, 44, 13308-13318.
DOI: 10.1039/D0NJ00657B - Design and virtual screening of novel fluoroquinolone analogs as effective mutant DNA GyrA inhibitors against urinary tract infection-causing fluoroquinolone resistant Escherichia coli
S. Balasubramaniyan, N.Irfan, A. Umamaheswari, A. Puratchikody. RSC Adv., 2018, 8, 23629-23647.
DOI : 10.1039/C8RA01854E