URAGUCHI, Daisuke

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URAGUCHI, Daisuke
Professor
Institute for Catalysis, Hokkaido University
ICReDD Fellow

About the Research

Research Theme

Organic chemistry, Catalysis

Keyword

Organocatalysis, Asymmetric Catalysis, Photocatalysis

Research Outline

We are challenging the control of active species (anions, radicals, and cations) involved in chemical reactions by creating novel molecules and eliciting the catalytic power inherent in the structure. In addition, we aim to create new chemical reactions through the experimental and theoretical understanding the behavior of molecules.

Representative Research Achievements

  • Urea as a Redox-active Directing Group under Asymmetric Photocatalysis of Iridium-Chiral Borate Ion Pairs
    D. Uraguchi, Y. Kimura, F. Ueoka, T. Ooi. J. Am. Chem. Soc.2020, 142, 19462-19467.
    DOI: 10.1021/jacs.0c09468
  • A Structurally Robust Chiral Borate Ion: Molecular Design, Synthesis, and Asymmetric Catalysis
    D. Uraguchi, F. Ueoka, N. Tanaka, T. Kizu, W. Takahashi, T. Ooi. Angew. Chem. Int. Ed., 2020, 59, 11456-11461.
    DOI: 10.1002/anie.202001637
  • Unveiling Latent Photoreactivity of Imines
    D. Uraguchi, Y. Tsuchiya, T. Ohtani, T. Enomoto, S. Masaoka, D. Yokogawa, T. Ooi. Angew. Chem. Int. Ed., 2020, 59, 3665-3670.
    DOI: 10.1002/anie.201913555
  • Catalyst-Directed Guidance of Sulfur-Substituted Enediolates to Stereoselective Carbon-Carbon Bond Formation with Aldehydes
    D. Uraguchi, K. Yamada, M. Sato, T. Ooi. J. Am. Chem. Soc., 2018, 140, 5110-5117.
    DOI: 10.1021/jacs.7b12949
  • Molecular Design, Synthesis, and Asymmetric Catalysis of a Hexacoordinated Chiral Phosphate Ion
    D. Uraguchi, H. Sasaki, Y. Kimura, T. Ito, T. Ooi. J. Am. Chem. Soc., 2018, 140, 2765-2768.
    DOI: 10.1021/jacs.7b13433

Publications

2024

  • Mechanism-Guided Development of Bifunctional Cyclooctenes as Active, Practical, and Light-Gated Bromination Catalysts
    T. Nagano, T. Shimazu, Y. Ono, K. Kaneko, S. Matsubara, M. Yamanaka, D. Uraguchi, K. Asano, Chem. Eur. J., 2024, ,
    DOI: 10.1002/chem.202404011
  • BODNs as Biocompatible Brominating Reagents: Visible-Light Photocatalytic Tyrosine Modification under Physiologically Favorable Conditions
    R. Yoshida, Y. Hori, D. Uraguchi, K. Asano, Chem. Commun., 2024, 60, 12381-12384
    DOI: 10.1039/d4cc04171b
  • Synthesis of Substituted Cyclooctenes through Cross-Coupling Reactions
    R. Murata, R. Yoshida, D. Uraguchi, K. Asano, Synlett, 2024, 36(01), 69-74
    DOI: 10.1055/a-2330-0819

2023

  • Trans-Cyclooctenes as Scavengers of Bromine Involved in Catalytic Bromination
    R. Murata, K. Shitamichi, M. Hiramatsu, S. Matsubara, D. Uraguchi, K. Asano, Chem. Eur. J., 2023, ,
    DOI: 10.1002/chem.202303399