About the Research
Research Theme
Organic chemistry, Catalysis
Keyword
Organocatalysis, Asymmetric Catalysis, Photocatalysis
Research Outline
We are challenging the control of active species (anions, radicals, and cations) involved in chemical reactions by creating novel molecules and eliciting the catalytic power inherent in the structure. In addition, we aim to create new chemical reactions through the experimental and theoretical understanding the behavior of molecules.
Representative Research Achievements
- Urea as a Redox-active Directing Group under Asymmetric Photocatalysis of Iridium-Chiral Borate Ion Pairs
D. Uraguchi, Y. Kimura, F. Ueoka, T. Ooi. J. Am. Chem. Soc., 2020, 142, 19462-19467.
DOI: 10.1021/jacs.0c09468 - A Structurally Robust Chiral Borate Ion: Molecular Design, Synthesis, and Asymmetric Catalysis
D. Uraguchi, F. Ueoka, N. Tanaka, T. Kizu, W. Takahashi, T. Ooi. Angew. Chem. Int. Ed., 2020, 59, 11456-11461.
DOI: 10.1002/anie.202001637 - Unveiling Latent Photoreactivity of Imines
D. Uraguchi, Y. Tsuchiya, T. Ohtani, T. Enomoto, S. Masaoka, D. Yokogawa, T. Ooi. Angew. Chem. Int. Ed., 2020, 59, 3665-3670.
DOI: 10.1002/anie.201913555 - Catalyst-Directed Guidance of Sulfur-Substituted Enediolates to Stereoselective Carbon-Carbon Bond Formation with Aldehydes
D. Uraguchi, K. Yamada, M. Sato, T. Ooi. J. Am. Chem. Soc., 2018, 140, 5110-5117.
DOI: 10.1021/jacs.7b12949 - Molecular Design, Synthesis, and Asymmetric Catalysis of a Hexacoordinated Chiral Phosphate Ion
D. Uraguchi, H. Sasaki, Y. Kimura, T. Ito, T. Ooi. J. Am. Chem. Soc., 2018, 140, 2765-2768.
DOI: 10.1021/jacs.7b13433
Publications
2024
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Mechanism-Guided Development of Bifunctional Cyclooctenes as Active, Practical, and Light-Gated Bromination Catalysts
, T. Shimazu, Y. Ono, K. Kaneko, S. Matsubara, M. Yamanaka, D. Uraguchi, K. Asano, Chem. Eur. J., 2024, ,
DOI: 10.1002/chem.202404011
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BODNs as Biocompatible Brominating Reagents: Visible-Light Photocatalytic Tyrosine Modification under Physiologically Favorable Conditions
, Y. Hori, D. Uraguchi, K. Asano, Chem. Commun., 2024, 60, 12381-12384
DOI: 10.1039/d4cc04171b
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Synthesis of Substituted Cyclooctenes through Cross-Coupling Reactions
, R. Yoshida, D. Uraguchi, K. Asano, Synlett, 2024, 36(01), 69-74
DOI: 10.1055/a-2330-0819
2023
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Trans-Cyclooctenes as Scavengers of Bromine Involved in Catalytic Bromination
, K. Shitamichi, M. Hiramatsu, S. Matsubara, D. Uraguchi, K. Asano, Chem. Eur. J., 2023, ,
DOI: 10.1002/chem.202303399