About the Research
Research Theme
Crystal engineering for enhanced stereoselectivity in topochemical reactions
Keyword
Topochemistry, Asymmetric synthesis, Solid-state chemistry, Crystal engineering
Research Outline
1. Crystal engineering to draw structure-property relationship between molecular packing and topochemical reactivity.
2. Develop generalised crystal-engineering strategies for enhanced stereoselectivity and rate acceleration in topochemical reactions.
Representative Research Achievements
- Fast self-healing in a layered molecular crystal mediated by stress-induced symmetry breaking
I. Ghosh, R. Biswas, M. Tanwar, S. Bhunia, K. Das, A. Torris, A. Mondal, V. Raghunathan, R. Kumar, C.M. Reddy, Nat. Commun., 2026, 17, 2525
DOI: 10.1038/s41467-026-68987-z - Structural origin of fracture-induced surface charges in piezoelectric pharmaceutical crystals for engineering bulk properties
K. Das, I. Ghosh, S. Chakraborty, A.G. Nambiar, S. Maji, S.K. Karan, D. Kumar, A.K. Bansal, C.M. Reddy, Nat. Commun., 2025, 16, 6858
DOI: 10.1038/s41467-025-58138-1