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Associate Professor
Faculty of Engineering, Hokkaido University
Related Website
ITO, Hajime Group
Principal Investigator
Faculty Members
Postdoctoral Fellows
Research Collaborators
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    KUBOTA, Koji
  • KUBO, Shotaro

About the Research

Research Theme

Development of New Reactions Using Mechanochemistry


Mechanochemistry, Ball Mill, Catalysis, Synthetic Method
Research History

See my CV.

Representative Research Achievements

  • Redox reactions of small organic molecules using ball milling and piezoelectric materials
    Kubota, K.*; Pang, Y.; Miura, A.; Ito, H.,* Science, 2019, 366, 1500
    DOI: 10.1126/science.aay8224
  • Mechanochemistry allows carrying out sensitive organometallic reactions in air: glove-box-and-Schlenk-line-free synthesis of oxidative addition complexes from aryl halides and palladium(0)
    Kubota, K.*; Takahashi, R.; Ito, H.,* Chem. Sci., 2019, 10, 5837
    DOI: 10.1039/C9SC01711A
  • Olefin-accelerated solid-state C-N cross-coupling reactions using mechanochemistry
    Kubota, K.*; Seo, T.; Koide, K.; Hasegawa, Y.; Ito, H.,* Nature Commun., 2019, 10, 111 
    DOI: 10.1038/s41467-018-08017-9
  • Solid-State Suzuki-Miyaura Cross-Coupling Reactions: Olefin-Accelerated C–C Coupling Using Mechanochemistry
    Seo, T.; Ishiyama, T.; Kubota, K.*; Ito, H.,* Chem. Sci., 2019, 10, 8202 
    DOI: 10.1039/C9SC02185J
  • Palladium Oxidative Addition Complexes for Peptide and Protein Cross-linking
    Kubota, K.; Dai, P.; Pentelute B. L.*; Buchwald S. L.,* J. Am. Chem. Soc., 2018, 140, 3128 
    DOI: 10.1021/jacs.8b00172

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