About the Research
Research Theme
Organic Chemistry
Keyword
Photochemistry, Data Science, Fluorine Chemistry
Research Outline
We are trying to recycle greenhouse gases such fluoroform and utlizing them as cheap feedstocks to synthesis useful fluorinated organic componds. Besides, we are also pursuing C-F bond functionalization using photochemistry.
Representative Research Achievements
- FLP-Catalyzed Monoselective C–F Functionalization in Polyfluorocarbons at Geminal or Distal Sites.
Gupta, R., Mandal, D., Jaiswal, A. K., & Young, R. D. Organic Letters, 2021, 23(5), 1915–1920.
DOI: 10.1021/acs.orglett.1c00346 - Frustrated Lewis-Pair-Meditated Selective Single Fluoride Substitution in Trifluoromethyl Groups.
Mandal, D., Gupta, R., Jaiswal, A. K., & Young, R. D. Journal of the American Chemical Society, 2020, 142(5), 2572–2578.
DOI: 10.1021/jacs.9b12167 - Nucleophilic Substitution of Aliphatic Fluorides via Pseudohalide Intermediates.
Jaiswal, A. K., Prasad, P. K., & Young, R. D. Chemistry – A European Journal, 2019, 25(25), 6290–6294.
DOI: 10.1002/chem.201806272 - Aluminum-Catalyzed Cross-Coupling of Silylalkynes with Aliphatic C–F Bonds.
Jaiswal, A. K., Goh, K. K. K., Sung, S., & Young, R. D. Organic Letters, 2017, 19(7), 1934–1937.
DOI: 10.1021/acs.orglett.7b00712
Related Research
- Mechanistic Exploration of N-Heterocyclic Carbene Boranes as the Hydrogen Atom Transfer Reagent in Selective Hydrodefluorination Reactions
- New avenue towards widely applicable indigo photoswitches – Combining experimental, computational and data-science approaches –
Publications
2024
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Mechanistic Exploration of N-Heterocyclic Carbene Boranes as the Hydrogen Atom Transfer Reagent in Selective Hydrodefluorination Reactions
, B. Skjelstad, S. Maeda, D. Huang, Acs Catalysis, 2024, 14, 17547–17555
DOI: 10.1021/acscatal.4c05092
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Accessing a Diverse Set of Functional Red-Light Photoswitches by Selective Copper-Catalyzed Indigo N-Arylation
, P. Saha, J. Jiang, K. Suzuki, A. Jasny, B. Schmidt, S. Maeda, S. Hecht, C. Huang, J. Am. Chem. Soc., 2024, 146, 31, 21367-21376
DOI: 10.1021/jacs.4c03543