About the Research
Research Theme
Development of New Reactions Using Mechanochemistry
Keyword
Research Outline
Now, I am focusing on the development of new reactions using mechanochemistry. Mechanochemistry, which uses mechanical energy to facilitate chemical reactions by grinding, stretching, shearing, or other types of mechanical action, has experienced explosive growth in the past two decades. It is re-emerging as a technique for organic synthesis, which was well known in the area of crystal engineering and polymorphism. Recently, mechanochemical synthesis becomes more and more prevalent and has been extensively exploited in materials science, polymer chemistry, inorganic synthesis, and organic synthesis due to its exclusive advantages including the avoidance of potentially harmful organic solvents and external heating, shorter reaction times, simpler operational handling, and improved or new selectivity.
Inspired by these benefits, I hope we can perform the reactions more easily and find many differences with traditional methods (solution-based method).
Representative Research Achievements
- Redox Reactions of Small Organic Molecules Using Ball Milling and Piezoelectric Materials
K. Kubota, Y. Pang, A. Miura, H. Ito, Science, 2019, 366, 1500
DOI: 10.1126/science.aay8224 - Iridium(I)-Catalyzed C-H Borylation in Air by Using Mechanochemistry
Y. Pang, T. Ishiyama, K. Kubota, H. Ito, Chem. Eur. J., 2019, 25, 4654
DOI: 10.1002/chem.201900685