研究紹介
研究テーマ
Characterization of cancer stem cells for effective drug development
キーワード
Cancer stem cells, Raman microscopy, Image processing
研究概要
Cancer stem cells are a subpopulation of cancer cells that play a crucial role in cancer development and progression, making their study important for understanding cancer biology. Raman microscopy and cell morphology analysis are powerful techniques that can enable us to study cancer stem cells at the molecular and cellular level. Despite their potential, the study of cancer stem cells using Raman microscopy and cell morphology analysis is still in its early stages.
My research is focused on identifying and characterizing cancer stem cells based on their distinct molecular and morphological features, enabling the development of more targeted cancer therapies.
代表的な研究成果
- Geometrical analysis identified morphological features of hydrogel-induced cancer stem cells in synovial sarcoma model cells. Zannatul Ferdous, Jean-Emmanuel Clément, Jian Ping Gong, Shinya Tanaka, Tamiki Komatsuzaki, Masumi Tsuda. Biochemical and Biophysical Research Communications, 2023, 642, 41-49.
DOI: 10.1016/j.bbrc.2022.12.040
関連する研究記事
業績一覧
2024年
-
Virological Characteristics of the SARS-CoV-2 Omicron XBB.1.5 Variant
, T. Irie, S. Deguchi, H. Yajima, M. Tsuda, H. Nasser, K. Mizuma, A. Plianchaisuk, S. Suzuki, K. Uriu, M. M. Begum, R. Shimizu, M. Jonathan, R. Suzuki, T. Kondo, H. Ito, A. Kamiyama, K. Yoshimatsu, M. Shofa, R. Hashimoto, Y. Anraku, K. T. Kimura, S. Kita, J. Sasaki, K. Sasaki-Tabata, K. Maenaka, N. Nao, L. Wang, Y. Oda, H. Sawa, R. Kawabata, Y. Watanabe, A. Sakamoto, N. Yasuhara, T. Suzuki, Y. Nakajima, Z. Ferdous, K. Shishido, Y. Mugita, O. Takahashi, K. Ichihara, Y. Kaku, N. Misawa, Z. Y. Guo, A. Hinay, Y. Kosugi, S. Fujita, J. M. Tolentino, L. Chen, L. Pan, M. Suganami, M. Chiba, R. Yoshimura, K. Yasuda, K. Iida, N. Ohsumi, A. P. Strange, Y. Shibatani, T. Nishiuchi, S. Tanaka, O. Putri, G. Joas, Y. Kim, D. Yamasoba, K. Yoshimura, K. Sadamasu, M. Nagashima, H. Asakura, I. Yoshida, S. Nakagawa, A. Takaori-Kondo, K. Shirakawa, K. Nagata, R. Nomura, Y. Horisawa, Y. Tashiro, Y. Kawai, T. Ueno, C. Motozono, M. Toyoda, T. Ikeda, A. Saito, K. Matsuno, J. Ito, K. Sato, T. Hashiguchi, K. Takayama, T. Fukuhara, G. P. Genotype Phenotype Japan, Nat. Commun., 2024, 15,
DOI: 10.1038/s41467-024-45274-3
2023年
-
Differentiability of Cell Types Enhanced by Detrending a Non-Homogeneous Pattern in a Line-Illumination Raman Microscope
, J. E. Clement, Z. Ferdous, K. Mochizuki, K. Tabata, J. N. Taylor, Y. Kumamoto, Y. Harada, T. Bocklitz, K. Fujita, T. Komatsuzaki, Analyst, 2023, Advance Article,
DOI: 10.1039/d3an00516j
-
Convergent Evolution of SARS-CoV-2 Omicron Subvariants Leading to the Emergence of BQ.1.1 Variant
, R. Suzuki, K. Uriu, Y. Itakura, J. Zahradnik, K. T. Kimura, S. Deguchi, L. Wang, S. Lytras, T. Tamura, I. Kida, H. Nasser, M. Shofa, M. M. Begum, M. Tsuda, Y. Oda, T. Suzuki, J. Sasaki, K. Sasaki-Tabata, S. Fujita, K. Yoshimatsu, H. Ito, N. Nao, H. Asakura, M. Nagashima, K. Sadamasu, K. Yoshimura, Y. Yamamoto, T. Nagamoto, J. Kuramochi, G. Schreiber, A. Saito, K. Matsuno, K. Takayama, T. Hashiguchi, S. Tanaka, T. Fukuhara, T. Ikeda, K. Sato, S. Suzuki, M. Kato, Z. Ferdous, H. Mouri, K. Shishido, N. Misawa, I. Kimura, Y. Kosugi, P. Lin, M. Suganami, M. Chiba, R. Yoshimura, K. Yasuda, K. Iida, N. Ohsumi, A. P. Strange, D. Sauter, S. Nakagawa, J. Q. Wu, Y. Watanabe, A. Sakamoto, N. Yasuhara, Y. Nakajima, H. Yajima, K. Shirakawa, A. Takaori-Kondo, K. Nagata, Y. Kazuma, R. Nomura, Y. Horisawa, Y. Tashiro, Y. Kawa, T. Irie, R. Kawabata, R. Shimizu, O. Takahashi, K. Ichihara, C. Motozono, M. Toyoda, T. Ueno, Y. Shibatani, T. Nishiuchi, G. P. J. Genotype Phenotype Japan, Nat. Commun., 2023, 14, 2671,
DOI: 10.1038/s41467-023-38188-z