About the Research
Research Theme
Development of light-responsive biofunctional molecules
Keyword
Chemical biology, Photochemistry
Research Outline
We develop functional molecules triggered by light in specific biological environments. Furthermore, we also aim to develop novel therapeutic agents by observing and controlling the activity and behavior of biofunctional molecules in vivo.
Representative Research Achievements
- Asymmetric bismuth-rhodamines as an activatable fluorogenic photosensitizer
A. Mukaimine, T. Hirayama, H. Nagasawa. Org. Biomol. Chem., 2021, 19, 3611–3619.
DOI: 10.1039/D0OB02456B - Bismuth-rhodamine: a new red light-excitable photosensitizer
T. Hirayama, A. Mukaimine, K. Nishigaki, H. Tsuboi, S. Hirosawa, K. Okuda, M. Ebihara, H. Nagasawa. Dalton Trans., 2017, 46, 15991–15995.
DOI: 10.1039/C7DT03194G