About the Research
Keyword
Stem cell biology, tissue regeneration, cancer, bioimaging, biomaterial
Research History
See my CV.
Representative Research Achievements
- Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine
Yu Muta, Yoshihisa Fujita, Kenta Sumiyama, Atsuro Sakurai, Makoto Mark Taketo, Tsutomu Chiba, Hiroshi Seno, Kazuhiro Aoki, Michiyuki Matsuda, Masamichi Imajo* (corresponding author), Nature Commun., 2018, 9, 2174
DOI: 10.1038/s41467-018-04527-8 - Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic acid Receptor Signaling in Colorectal Cancer Cells
Masamichi Imajo* (corresponding author), Kunio Kondoh, Takuya Yamamoto, Kei Nakayama, May Nakajima-Koyama, Eisuke Nishida, Mol. Cell. Biol., 2017, 37, e00012-17
DOI: 10.1128/MCB.00012-17 - HOXA5 counteracts stem cell traits by inhibiting Wnt signaling in colorectal cancer
Ordóñez-Morán, P., Dafflon, C., Imajo, M., Nishida, E., Huelsken, J*, Cancer Cell, 2015, 28, 815-829
DOI:10.1016/j.ccell.2015.11.001 - Dual role of YAP and TAZ in renewal of the intestinal epithelium
Masamichi Imajo* (corresponding author), Miki Ebisuya, Eisuke Nishida*, Nature Cell Biol., 2015, 17, 7-19
DOI: 10.1038/ncb3084 - A molecular mechanisms that links Hippo signalling to the inhibition of Wnt/β-catenin signaling
Masamichi Imajo, Koichi Miyatake, Akira Iimura, Atsumu Miyamoto, Eisuke Nishida*, EMBO J., 2012, 31, 1109-1122
DOI:10.1038/emboj.2011.487
Related Research
- Press Release Healing the brain: hydrogels enable neuronal tissue growth
- Mechanism for resistance to retinoid treatment in breast cancer revealed
Publications
2023
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Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
, Ebisu, Y, Sedlacík, T, Semba, S, Nonoyama, T, Kurokawa, T, Hirota, A, Takahashi, T, Yamaguchi, K, Imajo, M, Kato, H, Nishimura, T, Tanei, ZI, Tsuda, M, Nemoto, T, Gong, JP, Tanaka, S, Scientific Reports, 2023, 13, (1), Article number: 2233
DOI: 10.1038/s41598-023-28870-z
2022
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ERK MAP Kinase Signaling Regulates RAR Signaling to Confer Retinoid Resistance on Breast Cancer Cells
, J. E. Clement, S. Tanikawa, T. Nonoyama, T. Komatsuzaki, J. P. Gong, S. Tanaka, M. Imajo, Cancers, 2022, 14,
DOI: 10.3390/cancers14235890
2021
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Biomaterials for Intestinal Organoid Technology and Personalized Disease Modeling
, S. AlMusawi, A. S. Nateri, P. Ordonez-Moran, M. Imajo, Acta Biomaterialia, 2021, 132, 272-287
DOI: 10.1016/j.actbio.2021.05.010
2019
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Divergent Dynamics and Functions of ERK MAP Kinase Signaling in Development, Homeostasis and Cancer: Lessons from Fluorescent Bioimaging
, M. Tsuda, M. Imajo, Cancers, 2019, 11, 513
DOI: 10.3390/cancers11040513