辻 信弥

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辻 信弥
特任准教授
Co-PI (リストグループ)
ベンジャミン・リスト グループ
主任研究者
教員
  • thumbnail image
    辻 信弥
博士研究員
スタッフ
  • 山口 繭美

研究紹介

研究テーマ

不斉ブレンステッド酸・ルイス酸触媒

キーワード

不斉触媒、有機触媒
経歴

経歴書を参照願います。

MANABIYAコースの研修内容はこちらです。MANABIYA全般について詳しく知りたい方は、こちらをクリックしてください。

代表的な研究成果

  • Activation of olefins via asymmetric Brønsted acid catalysis
    N. Tsuji, J. L. Kennemur, T. Buyck, S. Lee, S. Prévost, P. S. J. Kaib, D. Bykov, C. Farès, B. List, Science, 2018, 359, 1501–1505
    DOI: 10.1126/science.aaq0445
  • Predicting Highly Enantioselective Catalysts Using Tunable Fragment Descriptors
    N. Tsuji, P. Sidorov, C. D. Zhu, Y. Nagata, T. Gimadiev, A. Varnek, B. List, Angew. Chem., Int. Ed., 2023, e202218659,
    DOI: 10.1002/anie.202218659
  • Catalytic asymmetric fragmentation of cyclopropanes
    R. K. Raut, S. Matsutani, F. Shi, S. Kataoka, M. Poje, B. Mitschke, S. Maeda, N. Tsuji*, B. List*, Science, 2024, 386, 225–230.
    DOI: 10.1126/science.adp9061

関連する研究記事

業績一覧

2025年

  • Catalytic Asymmetric (ene-endo)-Carbonyl-Ene Type Cyclizations
    L. Shi, N. Tsuji, C. Zhu, M. Leutzsch, J. Grimm, B. List, J. Am. Chem. Soc., 2025, 147, 38, 34225–34230
    DOI: 10.1021/jacs.5c11553
  • The Overlooked Stereoisomers of the Ionizable Lipid ALC315
    C. De, M. Tsuda, C. Zhu, S. Dehn, H. Hinrichs, N. Tsuji, H. Jin, H. Arase, S. Tanaka, B. List, J. Am. Chem. Soc., 2025, 147, 28595-28600
    DOI: 10.1021/jacs.5c08345

2024年

  • Catalytic Asymmetric Fragmentation of Cyclopropanes
    R. Raut, S. Matsutani, F. Shi, S. Kataoka, M. Poje, B. Mitschke, S. Maeda, N. Tsuji, B. List, Science, 2024, 386, 225-230
    DOI: 10.1126/science.adp9061
  • Highly Acidic Electron-Rich Brønsted Acids Accelerate Asymmetric Pictet-Spengler Reactions by Virtue of Stabilizing Cation-π Interactions
    M. Scharf, N. Tsuji, M. Lindner, M. Leutzsch, M. Lökov, E. Parman, I. Leito, B. List, J. Am. Chem. Soc., 2024, 146, Issue 41, 28339-28349
    DOI: 10.1021/jacs.4c09421
  • Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silacycles
    J. Han, N. Tsuji, H. Zhou, M. Leutzsch, B. List, Nat. Commun., 2024, 15, Article number: 5846
    DOI: 10.1038/s41467-024-49988-2
  • Catalytic Asymmetric Cationic Shifts of Aliphatic Hydrocarbons
    V. N. Wakchaure, W. DeSnoo, C. J. Laconsay, M. Leutzsch, N. Tsuji, D. J. Tantillo, B. List, Nature, 2024, 625,
    DOI: 10.1038/s41586-023-06826-7

2023年

  • A Primer on 2D Descriptors in Selectivity Modeling for Asymmetric Catalysis
    P. Sidorov, N. Tsuji, Chem. Eur. J., 2023, , e202302837
    DOI: 10.1002/chem.202302837
  • A Catalytic Asymmetric Hydrolactonization
    R. Maji, S. Ghosh, O. Grossmann, P. L. Zhang, M. Leutzsch, N. Tsuji, B. List, J. Am. Chem. Soc., 2023, 145, 16, 8788–8793
    DOI: 10.1021/jacs.3c01404
  • Organocatalytic DYKAT of Si-Stereogenic Silanes
    H. Zhou, R. Properzi, M. Leutzsch, P. Belanzoni, G. Bistoni, N. Tsuji, J. T. Han, C. D. Zhu, B. List, J. Am. Chem. Soc., 2023, 145, 9, 4994–5000
    DOI: 10.1021/jacs.3c00858
  • Predicting Highly Enantioselective Catalysts Using Tunable Fragment Descriptors
    N. Tsuji, P. Sidorov, C. D. Zhu, Y. Nagata, T. Gimadiev, A. Varnek, B. List, Angew. Chem., Int. Ed., 2023, e202218659,
    DOI: 10.1002/anie.202218659

2022年

  • Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers
    H. Zhou, J. T. Han, N. Nothling, M. M. Lindner, J. Jenniches, C. Kuhn, N. Tsuji, L. Zhang, B. List, J. Am. Chem. Soc., 2022, 144, 10156-10161
    DOI: 10.1021/jacs.2c04261

2021年

  • Confinement-Controlled, Either Syn- or Anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
    T. Amatov, N. Tsuji, R. Maji, L. Schreyer, H. Zhou, M. Leutzsch, B. List, J. Am. Chem. Soc., 2021, 143, 14475-14481
    DOI: 10.1021/jacs.1c07447
  • Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles
    P. L. Zhang, N. Tsuji, J. Ouyang, B. List, J. Am. Chem. Soc., 2021, 143, 675-680
    DOI: 10.1021/jacs.0c12042