About the Research
Research Theme
Asymmetric Brønsted acid/Lewis acid catalysis
Keyword
Asymmetric catalysis, Organocatalysis
Research History
See my CV.
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Representative Research Achievements
- Activation of olefins via asymmetric Brønsted acid catalysis
N. Tsuji, J. L. Kennemur, T. Buyck, S. Lee, S. Prévost, P. S. J. Kaib, D. Bykov, C. Farès, B. List, Science, 2018, 359, 1501–1505
DOI: 10.1126/science.aaq0445 - Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles
P. Zhang, N. Tsuji, J. Ouyang, B. List, J. Am. Chem. Soc., 2021, 143, 2, 675–680
DOI: 10.1021/jacs.0c12042 - Self-Assembly Asymmetric Organocatalysis: A Combined Experimental and Computational Investigation
M. R. Monaco, D. Fazzi, N. Tsuji, M. Leutzsch, S. Liao, W. Thiel, B. List, J. Am. Chem. Soc., 2016, 138, 44, 14740–14749
DOI: 10.1021/jacs.6b09179
Related Research
- Press Release Robots and A.I. team up to discover highly selective catalysts
- Asymmetric organocatalyst enables confinement-controlled syn/anti selective Mukaiyama aldolizations of propionaldehyde enolsilanes
Publications
2024
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Catalytic Asymmetric Cationic Shifts of Aliphatic Hydrocarbons
, W. DeSnoo, C. J. Laconsay, M. Leutzsch, N. Tsuji, D. J. Tantillo, B. List, Nature, 2024, 625,
DOI: 10.1038/s41586-023-06826-7
2023
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A Primer on 2D Descriptors in Selectivity Modeling for Asymmetric Catalysis
, N. Tsuji, Chem. Eur. J., 2023, , e202302837
DOI: 10.1002/chem.202302837
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A Catalytic Asymmetric Hydrolactonization
, S. Ghosh, O. Grossmann, P. L. Zhang, M. Leutzsch, N. Tsuji, B. List, J. Am. Chem. Soc., 2023, 145, 16, 8788–8793
DOI: 10.1021/jacs.3c01404
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Organocatalytic DYKAT of Si-Stereogenic Silanes
, R. Properzi, M. Leutzsch, P. Belanzoni, G. Bistoni, N. Tsuji, J. T. Han, C. D. Zhu, B. List, J. Am. Chem. Soc., 2023, 145, 9, 4994–5000
DOI: 10.1021/jacs.3c00858
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Predicting Highly Enantioselective Catalysts Using Tunable Fragment Descriptors
, P. Sidorov, C. D. Zhu, Y. Nagata, T. Gimadiev, A. Varnek, B. List, Angew. Chem., Int. Ed., 2023, ,
DOI: 10.1002/anie.202218659
2022
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Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers
, J. T. Han, N. Nothling, M. M. Lindner, J. Jenniches, C. Kuhn, N. Tsuji, L. Zhang, B. List, J. Am. Chem. Soc., 2022, 144, 10156-10161
DOI: 10.1021/jacs.2c04261
2021
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Confinement-Controlled, Either Syn- or Anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
, N. Tsuji, R. Maji, L. Schreyer, H. Zhou, M. Leutzsch, B. List, J. Am. Chem. Soc., 2021, 143, 14475-14481
DOI: 10.1021/jacs.1c07447
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Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles
, N. Tsuji, J. Ouyang, B. List, J. Am. Chem. Soc., 2021, 143, 675-680
DOI: 10.1021/jacs.0c12042