INOKUMA, Yasuhide

thumbnail image
INOKUMA, Yasuhide
Principal Investigator
Hokkaido University
Research Areas
Organic Chemistry, Supramolecular Chemistry
Related Website
Contact

inokuma atmark eng.hokudai.ac.jp

INOKUMA, Yasuhide Group
Principal Investigator
  • thumbnail image
    INOKUMA, Yasuhide
Faculty Members
Postdoctoral Fellows
Research Collaborators

About the Research

Research Theme

Development of functional materials from aliphatic polyketones as 'carbonyl ropes'

Keyword

carbonyl compounds, crystallography

Research Outline

Since function is largely determined by shape, my goal is to create molecules that can be shaped with ease. Inspired by clay ropes used in pottery, I employ mainly polyketone polymers of determinable lengths whose flexible nature allows for the creation of any imaginable molecular shape. In addition, the great wealth of knowledge on carbonyl group reactions that can act on these polyketones enables us to introduce many desirable modifications into our “molecular ropes”.

ICReDD is a wonderful opportunity to find applications for these molecules, and to predict useful shapes and modifications, through the collaboration with information scientists and computational chemists.

The Researcher’s Perspective

Watching people grow to become better and better than myself is a source of much fun to me. Therefore, I encourage my students to discuss and think for themselves, and doing science is a tool for that. But if that personal growth can also result in new materials or new chemical reactions, that’s even better!

For details on MANABIYA course topics, please follow this link. To learn more about MANABIYA in general, please click here.

Representative Research Achievements

  • Control over Coordination Self-Assembly of Flexible, Multidentate Ligands by Stepwise Metal Coordination of Isopyrazole Subunits
    Y. Ashida, Y. Manabe, S. Yoshioka, T. Yoneda, Y. Inokuma, Dalton Trans., 2019, 48, 818-822
    DOI : 10.1039/C8DT04935A
  • Oligoacetylacetones as Shapable Carbon Chains and Their Transformation to Oligoimines for Construction of Metal-organic Architectures
    M. Uesaka, Y. Saito, S. Yoshioka, Y. Domoto, M. Fujita, Y. Inokuma, Comms. Chem., 2018, 1, article number 23
    DOI : 10.1038/s42004-018-0021-3
  • Bioinspired Synthesis of Pentalene-based Chromophores from an Oligoketone Chain
    Y. Saito, M. Higuchi, S. Yoshioka, H. Senboku, Y. Inokuma, Chem. Commun., 2018, 54, 6788-6791
    DOI : 10.1039/C8CC02379D
  • Preparation and Guest-Uptake Protocol for a Porous Complex Useful for ‘Crystal-free’ Crystallography
    Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, M. Fujita, Nat. Protocols, 2014, 9, 246-252
    DOI : 10.1038/nprot.2014.007
  • X-ray Analysis on the Nanogram to Microgram Scale Using Porous Complexes
    Y. Inokuma, S. Yoshioka, J. Ariyoshi, T. Arai, Y. Hitora, K. Takada, S. Matsunaga, K. Rissanen, M. Fujita, Nature, 2013, 495, 461-466
    DOI : 10.1038/nature11990

Related Research

Publications

2021

  • Isopyrazole-Masked Tetraketone: Tautomerism and Functionalization for Fluorescent Metal Ligands
    H. Shirakura, Y. Manabe, C. Kasai, Y. Inaba, M. Tsurui, Y. Kitagawa, Y. Hasegawa, T. Yoneda, Y. Ide, Y. Inokuma, European Journal of Organic Chemistry, 2021, , 4345-4349
    DOI: 10.1002/ejoc.202100784
  • Calix 3 Pyrrole: A Missing Link in Porphyrin-Related Chemistry
    Y. Inaba, Y. Nomata, Y. Ide, J. Pirillo, Y. Hijikata, T. Yoneda, A. Osuka, J. L. Sessler, Y. Inokuma, J. Am. Chem. Soc., 2021, 143, 12355-12360
    DOI: 10.1021/jacs.1c06331
  • Insoluble Pi-Conjugated Polyimine as an Organic Adsorbent for Group 10 Metal Ions
    H. Shirakura, Y. Hijikata, J. Pirillo, T. Yoneda, Y. Manabe, M. Murugavel, Y. Ide, Y. Inokuma, European Journal of Inorganic Chemistry, 2021, , 1705-1708
    DOI: 10.1002/ejic.202100172

2020

  • Splitting and Reorientation of Pi-Conjugation by an Unprecedented Photo-Rearrangement Reaction
    Inaba, Y, Yoneda, T, Kitagawa, Y, Miyata, K, Hasegawa, Y, Inokuma, Y, Chem. Commun., 2020, 56, 348-351
    DOI: 10.1039/c9cc09062b
  • Spirosilicate Dimers of a Bowl-Shaped Diol Generated by Intramolecular Cyclization of an Aliphatic Tetraketone Chain
    Y. Inaba, Y. Inokuma, Chem. Lett., 2020, 49, 882-884
    DOI: 10.1246/cl.200299
  • Aliphatic Polyketones as Classic yet New Molecular Ropes for Structural Diversity in Organic Synthesis
    Y. Inokuma, T. Yoneda, Y. Ide, S. Yoshioka, Chem. Commun., 2020, 56, 9079-9093
    DOI: 10.1039/d0cc02977g
  • Modular Synthesis of Oligoacetylacetones via Site-Selective Silylation of Acetylacetone Derivatives
    P. Sarkar, Y. Inaba, H. Shirakura, T. Yoneda, Y. Inokuma, Org. Biomol. Chem., 2020, 18, 3297-3302
    DOI: 10.1039/d0ob00501k
  • Chiral Monolayers with Achiral Tetrapod Molecules on Highly Oriented Pyrolytic Graphite
    H. Asakawa, S. Matsui, Q. T. Trinh, H. Hirao, Y. Inokuma, T. Ogoshi, S. Tanaka, K. Komatsu, A. Ohta, T. Asakawa, T. Fukuma, J. Phys. Chem. C, 2020, 124, 7760-7767
    DOI: 10.1021/acs.jpcc.9b11246
  • Supramolecular Conformational Control of Aliphatic Oligoketones by Rotaxane Formation
    Y. Manabe, K. Wada, Y. Baba, T. Yoneda, T. Ogoshi, Y. Inokuma, Org. Lett., 2020, 22, 3224-3228
    DOI: 10.1021/acs.orglett.0c01010
  • Luminescent Coordination Polymers Constructed from a Flexible, Tetradentate Diisopyrazole Ligand and Copper(I) Halides
    T. Yoneda, C. Kasai, Y. Manabe, M. Tsurui, Y. Kitagawa, Y. Hasegawa, P. Sarkar, Y. Inokuma, Chem. Asian J., 2020, 15, 601-605
    DOI: 10.1002/asia.201901682

2019

  • Control over Coordination Self-Assembly of Flexible, Multidentate Ligands by Stepwise Metal Coordination of Isopyrazole Subunits
    Y. Ashida, Y. Manabe, S. Yoshioka, T. Yoneda, Y. Inokuma, Dalton Trans., 2019, 48, 818-822
    DOI: 10.1039/c8dt04935a
  • Aliphatic Polyketones as Shapable Molecular Chains
    Y. Inokuma, J. Syn. Org. Chem. Jpn., 2019, 77, 1078-1085
    DOI: 10.5059/yukigoseikyokaishi.77.1078
  • Two-Step Transformation of Aliphatic Polyketones into π-Conjugated Polyimines
    Y. Manabe, M. Uesaka, T. Yoneda, Y. Inokuma, J. Org. Chem., 2019, 84, 9957-9964
    DOI: 10.1021/acs.joc.9b01119