津田 真寿美

津田真寿美

津田真寿美

准教授

北海道大学大学院医学研究院

バイオマテリアルによる癌の新規診断治療法および革新的再生医療の開発

癌、癌幹細胞、分子標的治療、遺伝子診断、再生医療、バイオマテリアル

バイオマテリアルを用いた細胞動態や生体反応性の解析により、疾患を深く理解し、癌の新規診断治療法の開発、革新的な再生医療の確立など、医療への応用を目指しています。

Exosomes containing ErbB2/CRK induce vascular growth in premetastatic niches and promote metastasis of bladder cancer
Yoshida K, Tsuda M, Matsumoto R, Semba S, Wang L, Sugino H, Tanino M, Kondo T, Tanabe K, Tanaka S., Cancer Sci, 2019, 110, 2119-2132
DOI: 10.1111/cas.14080
A Ca(2+)-dependent signaling circuit regulates influenza A virus internalization and infection
Fujioka Y, Tsuda M, Nanbo A, Hattori T, Sasaki J, Sasaki T, Miyazaki T, Ohba Y., Nat Commun, 2013, 4, 2763
DOI: 10.1038/ncomms3763
Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration
Watanabe T, Tsuda M, Makino Y, Konstantinou T, Nishihara H, Majima T, Minami A, Feller SM, Tanaka S., Cell Res, 2009, 19, 638-650
DOI: 10.1038/cr.2009.40
TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition
Tsuda M, Davis IJ, Argani P, Shukla N, McGill GG, Nagai M, Saito T, Laé M, Fisher DE, Ladanyi M., Cancer Res, 2007, 67, 919-929
DOI: 10.1158/0008-5472.CAN-06-2855
Induction of p21(WAF1/CIP1) by human synovial sarcoma-associated chimeric oncoprotein SYT-SSX1
Tsuda M, Watanabe T, Seki T, Kimura T, Sawa H, Minami A, Akagi T, Isobe K, Nagashima K, Tanaka S., Oncogene, 2005, 24, 7984-7990
DOI: 10.1038/sj.onc.1208942